Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0T3ZS
|
|||
Former ID |
DNC010544
|
|||
Drug Name |
(+/-)-2-(4'-Benzyloxyphenyl)thiomorpholin-5-one
|
|||
Synonyms |
CHEMBL598394; BDBM50307363
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C17H17NO2S
|
|||
Canonical SMILES |
C1C(SCC(=O)N1)C2=CC=C(C=C2)OCC3=CC=CC=C3
|
|||
InChI |
1S/C17H17NO2S/c19-17-12-21-16(10-18-17)14-6-8-15(9-7-14)20-11-13-4-2-1-3-5-13/h1-9,16H,10-12H2,(H,18,19)
|
|||
InChIKey |
WREDZZPMENXHRK-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation via tryptamine | ||||
Dopamine degradation | ||||
Putrescine degradation III | ||||
Noradrenaline and adrenaline degradation | ||||
KEGG Pathway | Glycine, serine and threonine metabolism | |||
Arginine and proline metabolism | ||||
Histidine metabolism | ||||
Tyrosine metabolism | ||||
Phenylalanine metabolism | ||||
Tryptophan metabolism | ||||
Drug metabolism - cytochrome P450 | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Dopaminergic synapse | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Alcoholism | ||||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5-Hydroxytryptamine degredation | ||||
Dopamine receptor mediated signaling pathway | ||||
Pathway Interaction Database | Alpha-synuclein signaling | |||
WikiPathways | Tryptophan metabolism | |||
Dopamine metabolism | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
---|---|---|---|---|
REF 1 | 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1388-95. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.