Drug Information
Drug General Information | Top | |||
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Drug ID |
D0SJ1U
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Drug Name |
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 8
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Synonyms |
PMID26815044-Compound-72
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Drug Type |
Small molecular drug
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Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
Melasma [ICD-11: ED60.1] | Patented | [1] | ||
Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C12H11NO4
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Canonical SMILES |
COC1=C(C=C(C=C1)C=C2CC(=O)NC2=O)O
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InChI |
1S/C12H11NO4/c1-17-10-3-2-7(5-9(10)14)4-8-6-11(15)13-12(8)16/h2-5,14H,6H2,1H3,(H,13,15,16)/b8-4+
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InChIKey |
NXKPYDPDZWALNH-XBXARRHUSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. |
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