Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R1GF
|
|||
| Former ID |
DNC006006
|
|||
| Drug Name |
2-[(biphenyl-4-carbonyl)-amino]-benzoic acid
|
|||
| Synonyms |
2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid; 94578-69-5; AC1LIZYF; 2-[(4-phenylbenzoyl)amino]benzoic Acid; Oprea1_107922; CHEMBL370865; SCHEMBL14075233; BDBM16094; MolPort-000-468-692; ZINC499675; STK068761; BBL015607; AKOS002229873; MCULE-9626131737; 2-[(4-phenylbenzene)amido]benzoic acid; ST50103720; H3372; 2-[(4-phenylphenyl)carbonylamino]benzoic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H15NO3
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC=CC=C3C(=O)O
|
|||
| InChI |
1S/C20H15NO3/c22-19(21-18-9-5-4-8-17(18)20(23)24)16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
|
|||
| InChIKey |
WXLRBDMDGLLZRS-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Bioorg Med Chem Lett. 2006 Jan 1;16(1):88-92. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.