Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q9ZN
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| Former ID |
DNC007929
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| Drug Name |
3-(4-(benzyloxy)-3,5-dibromophenyl)propanoic acid
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| Synonyms |
benzyl derivative, 8; CHEMBL402713; BDBM18888; 3-[4-(benzyloxy)-3,5-dibromophenyl]propanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H14Br2O3
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| Canonical SMILES |
C1=CC=C(C=C1)COC2=C(C=C(C=C2Br)CCC(=O)O)Br
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| InChI |
1S/C16H14Br2O3/c17-13-8-12(6-7-15(19)20)9-14(18)16(13)21-10-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2,(H,19,20)
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| InChIKey |
ZCVQDNGOBFARHQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid hormone receptor alpha (THRA) | Target Info | Inhibitor | [1] |
| Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Thyroid hormone signaling pathway | ||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | Endochondral Ossification | |||
| Nuclear Receptors | ||||
| SIDS Susceptibility Pathways | ||||
| Hematopoietic Stem Cell Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2018-21. | |||
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