Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Q9UO
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Former ID |
DNC000714
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Drug Name |
GW-311616
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Synonyms |
XVDWNSFFSMWXJJ-BDRHRQAXSA-N; UNII-HN0T99OO4V component XVDWNSFFSMWXJJ-BDRHRQAXSA-N; N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl) ethyl]amino]methyl]phenyl]-2E-2-propenamide D-(-)-lactate salt; n-hydroxy-3-[4-[[[2-(2-methyl-1h-indol-3-yl)ethyl]amino]methyl]phenyl]-2e-2-propenamide d-(-)-lactate salt
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C19H31N3O4S
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Canonical SMILES |
CC(C)C1C2C(CCN2C(=O)C=CCN3CCCCC3)N(C1=O)S(=O)(=O)C
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InChI |
1S/C19H31N3O4S/c1-14(2)17-18-15(22(19(17)24)27(3,25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20/h7-8,14-15,17-18H,4-6,9-13H2,1-3H3/b8-7+/t15-,17+,18-/m1/s1
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InChIKey |
NDNKNUMSTIMSHQ-URZKGLGPSA-N
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CAS Number |
CAS 198062-54-3
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Neutrophil elastase (NE) | Target Info | Inhibitor | [1] |
KEGG Pathway | Transcriptional misregulation in cancer | |||
Systemic lupus erythematosus | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
C-MYB transcription factor network | ||||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||
Human Complement System | ||||
Degradation of collagen |
References | Top | |||
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REF 1 | Neutrophil elastase inhibitors as treatment for COPD. Expert Opin Investig Drugs. 2002 Jul;11(7):965-80. |
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