Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q5TH
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| Former ID |
DIB013238
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| Drug Name |
XR-5944
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| Synonyms |
MLN-944; XR-11576 analogs; XR-5000 analogs; XR-5942
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| Drug Type |
Small molecular drug
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| Indication | Gastric adenocarcinoma [ICD-11: 2B72; ICD-9: 151] | Phase 1 | [1] | |
| Company |
Xenova Group plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C34H34N8O2
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| Canonical SMILES |
CC1=C2C(=CC=C1)N=C3C=CC=C(C3=N2)C(=O)NCCNCCNCCNC(=O)C4=CC=CC5=NC6=CC=CC(=C6N=C54)C
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| InChI |
1S/C34H34N8O2/c1-21-7-3-11-25-29(21)41-31-23(9-5-13-27(31)39-25)33(43)37-19-17-35-15-16-36-18-20-38-34(44)24-10-6-14-28-32(24)42-30-22(2)8-4-12-26(30)40-28/h3-14,35-36H,15-20H2,1-2H3,(H,37,43)(H,38,44)
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| InChIKey |
SFOADSRLCHRTKT-UHFFFAOYSA-N
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| CAS Number |
CAS 343247-32-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase II (TOP2) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antitumor activity of XR5944, a novel and potent topoisomerase poison. Anticancer Drugs. 2001 Apr;12(4):359-67. | |||
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