Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P7RN
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| Former ID |
DNC007978
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| Drug Name |
1-(4-fluorophenyl)-2-(phenylsulfonyl)ethanone
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| Synonyms |
CHEMBL238832; 41024-58-2; Ethanone, 1-(4-fluorophenyl)-2-(phenylsulfonyl)-; 1-(4-fluorophenyl)-2-(phenylsulfonyl)-1-ethanone; 1-(4-fluorophenyl)-2-(phenylsulfonyl)ethanone; AC1LS74Y; CTK1D4107; DTXSID90363277; MolPort-002-876-867; ZINC1396918; BDBM50212525; AKOS005098035; MCULE-9386710722; 7H-334S; KS-00001Z92; 4'-Fluoro-alpha-(phenylsulfonyl)acetophenone; 2-(benzenesulfonyl)-1-(4-fluorophenyl)ethanone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H11FO3S
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)CC(=O)C2=CC=C(C=C2)F
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| InChI |
1S/C14H11FO3S/c15-12-8-6-11(7-9-12)14(16)10-19(17,18)13-4-2-1-3-5-13/h1-9H,10H2
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| InChIKey |
FCXNRTNBPQUTBL-UHFFFAOYSA-N
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| CAS Number |
CAS 41024-58-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. | |||
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