Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P7EK
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| Former ID |
DAP000874
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| Drug Name |
Mannitol
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| Synonyms |
Diosmol; Hexahydroxyhexane; Invenex; Isotol; MTL; Manita; Mannazucker; Mannidex; Mannigen; Mannistol; Mannit; Mannite; Osmitrol; Osmofundin; Osmosal; Resectisol; Cordycepic acid; Cpd without stereochemical designation; Manna sugar; Mannitol [USAN]; Marine Crystal; Resectisol In Plastic Container; M0044; Mannidex 16700; Mannogem 2080; D-mannite; D-mannitol; DL-Mannitol; MANNITOL 25%; Maniton-S; Mannitol (USP); Mannitol (VAN); Mannitol 10%; Mannitol 10% In Plastic Container; Mannitol 15%; Mannitol 15% In Plastic Container; Mannitol 20%; Mannitol 20% In Plastic Container; Mannitol 5%; Mannitol 5% In Plastic Container; OSMITROL 10% IN WATER IN PLASTIC CONTAINER; OSMITROL 15% IN WATER IN PLASTIC CONTAINER; OSMITROL 20% IN WATER IN PLASTIC CONTAINER; OSMITROL 5% IN WATER IN PLASTIC CONTAINER; Osmitrol (TN); Osmitrol 10% In Water; Osmitrol 15% In Water; Osmitrol 20% In Water; Osmitrol 5% In Water; SDM No. 35; SORBITOL-MANNITOL IN PLASTIC CONTAINER; Sorbitol-Mannitol; D-Mannitol (JP15); MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER; D-(-)-Mannitol; ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D; MANNITOL 15% DEXTROSE 5% IN SODIUM CHLORIDE 0.45%; MANNITOL 5% DEXTROSE 5% IN SODIUM CHLORIDE 0.12%; (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; (L)-Mannitol
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| Drug Type |
Small molecular drug
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| Indication | Bronchiectasis [ICD-11: CA24; ICD-10: J47] | Approved | [1], [2] | |
| Renal failure [ICD-11: GB60-GB6Z] | Approved | [1], [2] | ||
| Therapeutic Class |
Sweetening Agents
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| Structure |
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Download2D MOL |
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| Formula |
C6H14O6
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| Canonical SMILES |
C(C(C(C(C(CO)O)O)O)O)O
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| InChI |
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
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| InChIKey |
FBPFZTCFMRRESA-KVTDHHQDSA-N
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| CAS Number |
CAS 69-65-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2928, 3682, 829269, 831961, 831967, 7847130, 7889067, 8025969, 8025992, 8145744, 8153931, 11528330, 12088020, 15195196, 16045072, 22435040, 24779011, 24860225, 24882727, 24882728, 24882729, 24896586, 24896902, 24897257, 24897341, 24897346, 26757663, 29225247, 46499979, 46506446, 48413961, 48416194, 48416764, 48423215, 49830006, 49990266, 53789262, 56310769, 56310961, 56311311, 56311364, 56311415, 56313258, 56320903, 56322640, 57323291, 57647519, 57648837, 57651947, 57651948
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| ChEBI ID |
CHEBI:16899
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| ADReCS Drug ID | BADD_D01349 | |||
| SuperDrug ATC ID |
A06AD16; B05BC01; B05CX04; R05CB16
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| SuperDrug CAS ID |
cas=000069658
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aspergillus Mannitol 2-dehydrogenase (Asperg M2DH) | Target Info | Activator | [3] |
| Aspergillus Mannitol-1-phosphate 5-dehydrogenase (Asperg mpdA) | Target Info | Activator | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 016080. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies o... Chem Biol Interact. 2009 Mar 16;178(1-3):274-82. | |||
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