Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OX9E
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| Drug Name |
US9127005, P0L
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| Synonyms |
CHEMBL3902347; SCHEMBL11991856; BDBM179736; US9127005, P0L
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H29FN4O2
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| Canonical SMILES |
CC(CN1CCC2(CC1)C(CNC2=O)C3=CC=C(C=C3)F)NC(=O)C4=CC5=CC=CC=C5N=C4
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| InChI |
1S/C27H29FN4O2/c1-18(31-25(33)21-14-20-4-2-3-5-24(20)29-15-21)17-32-12-10-27(11-13-32)23(16-30-26(27)34)19-6-8-22(28)9-7-19/h2-9,14-15,18,23H,10-13,16-17H2,1H3,(H,30,34)(H,31,33)/t18-,23+/m0/s1
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| InChIKey |
VALMDDHRZJXVOR-FDDCHVKYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase D1 (PLD1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phospholipase D1 (PLD1) | Target's Patent Info | [1] | |
| BioCyc | Phospholipases | |||
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Ether lipid metabolism | ||||
| Metabolic pathways | ||||
| Ras signaling pathway | ||||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Endocytosis | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Glutamatergic synapse | ||||
| GnRH signaling pathway | ||||
| Pathways in cancer | ||||
| Pancreatic cancer | ||||
| Choline metabolism in cancer | ||||
| Panther Pathway | Angiogenesis | |||
| Ras Pathway | ||||
| Pathway Interaction Database | RhoA signaling pathway | |||
| Arf6 trafficking events | ||||
| CDC42 signaling events | ||||
| Arf6 downstream pathway | ||||
| mTOR signaling pathway | ||||
| ErbB1 downstream signaling | ||||
| IL8- and CXCR1-mediated signaling events | ||||
| Alpha-synuclein signaling | ||||
| Reactome | Role of phospholipids in phagocytosis | |||
| WikiPathways | EGF/EGFR Signaling Pathway | |||
| TSH signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Isoform selective phospholipase D inhibitors. US9127005. | |||
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