Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0O1QT
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| Former ID |
DNC004469
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| Drug Name |
6-Amino-benzothiazole-2-sulfonic acid amide
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| Synonyms |
6-aminobenzo[d]thiazole-2-sulfonamide; 6-Amino-2-benzothiazolesulfonamide; 94641-11-9; MR69RTSOVN; UNII-MR69RTSOVN; CHEMBL35118; Aminozolamide; AC1L3QBY; 6-Amino-benzothiazole-2-sulfonic acid amide; SCHEMBL9459715; OFSGGVHHSMAUEI-UHFFFAOYSA-N; 6-aminobenzothiazole-2-sulfonamide; ZINC5162075; BDBM50079035; 2-Benzothiazolesulfonamide, 6-amino-; AKOS022656973; FCH1394039; 6-amino-1,3-benzothiazole-2-sulfonamide; AX8292464
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H7N3O2S2
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| Canonical SMILES |
C1=CC2=C(C=C1N)SC(=N2)S(=O)(=O)N
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| InChI |
1S/C7H7N3O2S2/c8-4-1-2-5-6(3-4)13-7(10-5)14(9,11)12/h1-3H,8H2,(H2,9,11,12)
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| InChIKey |
OFSGGVHHSMAUEI-UHFFFAOYSA-N
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| CAS Number |
CAS 94641-11-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase I (CA-I) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides co... J Med Chem. 1999 Jul 15;42(14):2641-50. | |||
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