Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0N0LB
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| Former ID |
DIB018051
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| Drug Name |
zoxazolamine
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| Synonyms |
Zoxazolamine; 61-80-3; 2-Amino-5-chlorobenzoxazole; 5-chlorobenzo[d]oxazol-2-amine; 5-Chloro-1,3-benzoxazol-2-amine; Flexin; 2-Benzoxazolamine, 5-chloro-; Contrazole; Deflexol; Flexilon; Zoxamin; Zoxine; USAF MA-12; McN-485; 5-Chloro-2-benzoxazolamine; Zossazolamina [DCIT]; C7H5ClN2O; Zoxazolaminum [INN-Latin]; Zoxazolamina [INN-Spanish]; NSC 24995; UNII-9DOW362Q29; BENZOXAZOLE, 2-AMINO-5-CHLORO-; CHEBI:35053; EINECS 200-519-4; MLS002639033; AI3-63120; YGCODSQDUUUKIV-UHFFFAOYSA-N; 9DOW362Q29; 2-Amino-5-chlorobenzoxazole, 97%
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| Drug Type |
Small molecular drug
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| Indication | Multiple myeloma [ICD-11: 2A83; ICD-10: C90; ICD-9: 203] | Terminated | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C7H5ClN2O
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| Canonical SMILES |
C1=CC2=C(C=C1Cl)N=C(O2)N
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| InChI |
1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)
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| InChIKey |
YGCODSQDUUUKIV-UHFFFAOYSA-N
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| CAS Number |
CAS 61-80-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
86322, 854086, 3131904, 5460817, 6514680, 8002084, 8153820, 10321836, 10530067, 11112165, 11342038, 11362221, 11364643, 11367205, 11369767, 11372764, 11374347, 11377929, 11466356, 11467476, 11484578, 11485992, 11487623, 11488587, 11491478, 11492439, 11495563, 14772550, 24890884, 26612674, 26679362, 26748934, 26748935, 29225112, 47276638, 47425318, 47574394, 47647535, 47721635, 47870773, 47870774, 48095557, 48435632, 49698841, 49892065, 50107487, 50107488, 51072094, 53312179, 56463707
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| ChEBI ID |
CHEBI:35053
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium-activated potassium channel KCa2.2 (KCNN2) | Target Info | Activator | [2] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2327). | |||
| REF 2 | Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds. J Pharmacol Exp Ther. 2001 Mar;296(3):683-9. | |||
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