Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0MT3J
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| Drug Name |
Benzimidazole derivative 4
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| Synonyms |
PMID26815044-Compound-43
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| Drug Type |
Small molecular drug
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| Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
| Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
| Melasma [ICD-11: ED60.1] | Patented | [1] | ||
| Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
| Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
| Structure |
 |
Download2D MOL |
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| Formula |
C15H14N2O3
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| Canonical SMILES |
COC1=CC(=CC(=C1O)OC)C2=NC3=CC=CC=C3N2
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| InChI |
1S/C15H14N2O3/c1-19-12-7-9(8-13(20-2)14(12)18)15-16-10-5-3-4-6-11(10)17-15/h3-8,18H,1-2H3,(H,16,17)
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| InChIKey |
LEEVVCNLICRBQX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. | |||
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