Drug Information
Drug General Information | Top | |||
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Drug ID |
D0K6BI
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Former ID |
DIB019412
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Drug Name |
PMID22115617C2c
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Synonyms |
TMCB; 905105-89-7; TMCB/; GTPL8140; DTXSID50677589; MolPort-019-939-193; BS0265; BDBM50359846; ZINC58638742; ABP000318; AKOS024457742; K66
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C11H9Br4N3O2
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Canonical SMILES |
CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br
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InChI |
1S/C11H9Br4N3O2/c1-17(2)11-16-9-7(14)5(12)6(13)8(15)10(9)18(11)3-4(19)20/h3H2,1-2H3,(H,19,20)
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InChIKey |
PHAOTASRLQMKBE-UHFFFAOYSA-N
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CAS Number |
CAS 905105-89-7
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Casein kinase II alpha (CSNK2A1) | Target Info | Inhibitor | [1] |
Casein kinase II alpha prime (CSNK2A2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Ribosome biogenesis in eukaryotes | |||
NF-kappa B signaling pathway | ||||
Wnt signaling pathway | ||||
Adherens junction | ||||
Tight junction | ||||
Measles | ||||
Herpes simplex infection | ||||
Epstein-Barr virus infection | ||||
NetPath Pathway | FSH Signaling Pathway | |||
Pathway Interaction Database | BCR signaling pathway | |||
Atypical NF-kappaB pathway | ||||
DNA-PK pathway in nonhomologous end joining | ||||
Presenilin action in Notch and Wnt signaling | ||||
Role of Calcineurin-dependent NFAT signaling in lymphocytes | ||||
E-cadherin signaling in the nascent adherens junction | ||||
Lissencephaly gene (LIS1) in neuronal migration and development | ||||
PDGFR-alpha signaling pathway | ||||
Signaling mediated by p38-alpha and p38-beta | ||||
Alpha-synuclein signaling | ||||
Reactome | Condensation of Prometaphase Chromosomes | |||
WikiPathways | Mitotic Prometaphase | |||
BDNF signaling pathway | ||||
TNF alpha Signaling Pathway | ||||
L1CAM interactions |
References | Top | |||
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REF 1 | CK2alpha and CK2alpha' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives. Eur J Med Chem. 2012 Jan;47(1):345-50. |
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