Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K5NQ
|
|||
| Former ID |
DNC005673
|
|||
| Drug Name |
N-[4-(trifluoromethyl)phenyl]sulfamide
|
|||
| Synonyms |
N-[4-(trifluoromethyl)phenyl]sulfamide; CHEMBL167179; N-[4-(trifluoromethyl)phenyl]sulfuric diamide; 556068-13-4; (4-trifluoromethylphenyl)sulfamide; SCHEMBL1645153; ZINC13488092; BDBM50124177; AKOS027393975; KB-300897; 79478-EP2305698A2; 79478-EP2305696A2; 79478-EP2305697A2
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C7H7F3N2O2S
|
|||
| Canonical SMILES |
C1=CC(=CC=C1C(F)(F)F)NS(=O)(=O)N
|
|||
| InChI |
1S/C7H7F3N2O2S/c8-7(9,10)5-1-3-6(4-2-5)12-15(11,13)14/h1-4,12H,(H2,11,13,14)
|
|||
| InChIKey |
LTJDGKNETMQCBO-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase I (CA-I) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxy... Bioorg Med Chem Lett. 2005 May 2;15(9):2353-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.