Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K4VN
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| Former ID |
DIB011127
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| Drug Name |
Molecule 21
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| Synonyms |
EP3 antagonists (pain/ uterine disease), Ono Pharmaceutical; Prostaglandin-E receptor 3 antagonists (pain/ uterine disease); Prostaglandin-E receptor 3 antagonists (pain/ uterine disease), Ono Pharmaceutical
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| Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
| Company |
Ono Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E2 receptor EP3 (PTGER3) | Target Info | Antagonist | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Regulation of lipolysis in adipocytes | ||||
| Pathways in cancer | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 342). | |||
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