Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J4UO
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| Drug Name |
Macrocycle derivative 3
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| Synonyms |
PMID30107136-Compound-Example67
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| Drug Type |
Small molecule immunotherapy
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| Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
| Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
| Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
| Company |
Bristol-Myers Squibb Company
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| Structure |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CD80-PD-L1 interaction (CD80/PD-L1 PPI) | Target Info | Inhibitor | [1] |
| PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | CD80-PD-L1 interaction (CD80/PD-L1 PPI) | Target's Patent Info | [1] | |
| PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] | ||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. | |||
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