Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J0YB
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| Former ID |
DNC007614
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| Drug Name |
1-adamantan-1-yl-3-(2-hydroxyethyl)urea
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| Synonyms |
1-adamantan-1-yl-3-(2-hydroxyethyl)urea; CHEMBL398166; 120615-92-1; NSC98656; 1-(1-adamantyl)-3-(2-hydroxyethyl)urea; AC1L6ASW; Oprea1_805585; CTK8A5210; MolPort-000-709-916; HMS1608K05; ZINC1643992; STK862338; BDBM50223393; IMED57309943; NSC-98656; AKOS023552817; AKOS001482962; MCULE-6824900815; N-1-adamantyl-N'-(2-hydroxyethyl)urea; EN300-234857; SR-01000396891; SR-01000396891-1; F0266-0451
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H22N2O2
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| Canonical SMILES |
C1C2CC3CC1CC(C2)(C3)NC(=O)NCCO
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| InChI |
1S/C13H22N2O2/c16-2-1-14-12(17)15-13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11,16H,1-8H2,(H2,14,15,17)
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| InChIKey |
BBHYFNMMUBVBEX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Soluble epoxide hydrolase (EPHX2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Peroxisome | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Metapathway biotransformation | |||
| Arachidonate Epoxygenase / Epoxide Hydrolase | ||||
| Arachidonic acid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic prope... J Med Chem. 2007 Oct 18;50(21):5217-26. | |||
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