Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IL8R
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| Former ID |
DIB015094
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| Drug Name |
A-93178
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| Synonyms |
A-93178.5
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| Indication | Allergy [ICD-11: 4A80-4A85; ICD-10: T78.4; ICD-9: 995.3] | Terminated | [1] | |
| Company |
Abbott Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H28N2O4
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| Canonical SMILES |
CC(=NOC(C1CCCCC1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O
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| InChI |
1S/C26H28N2O4/c1-18(26(29)30)28-32-25(20-8-3-2-4-9-20)21-12-15-23(16-13-21)31-17-22-14-11-19-7-5-6-10-24(19)27-22/h5-7,10-16,20,25H,2-4,8-9,17H2,1H3,(H,29,30)/b28-18-
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| InChIKey |
USBHSZPRMPADOE-VEILYXNESA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase activating protein (FLAP) | Target Info | Modulator | [1] |
| NetPath Pathway | IL4 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| WikiPathways | Nuclear Receptors Meta-Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Characterization of A-93178, an iminoxy-quinoline inhibitor of leukotriene biosynthesis. Adv Exp Med Biol. 1997;433:91-4. | |||
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