Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0IK2S
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| Former ID |
DNC010317
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| Drug Name |
(+/-)-7-fluoro-2-phenylchroman-4-one
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| Synonyms |
7-Fluoroflavanone; 4H-1-Benzopyran-4-one, 7-fluoro-2,3-dihydro-2-phenyl-; 98769-92-7; 7-fluoro-flavanone; AC1NRPFB; ACMC-20m2iw; CHEMBL596693; SCHEMBL10360962; CTK3G7728; DTXSID20414862; SZNYRENOXQIQMR-UHFFFAOYSA-N; 7-fluoro-2-phenyl-chroman-4-one; AKOS030553463
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11FO2
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| Canonical SMILES |
C1C(OC2=C(C1=O)C=CC(=C2)F)C3=CC=CC=C3
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| InChI |
1S/C15H11FO2/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14H,9H2
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| InChIKey |
SZNYRENOXQIQMR-UHFFFAOYSA-N
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| CAS Number |
CAS 98769-92-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation via tryptamine | ||||
| Dopamine degradation | ||||
| Putrescine degradation III | ||||
| Noradrenaline and adrenaline degradation | ||||
| KEGG Pathway | Glycine, serine and threonine metabolism | |||
| Arginine and proline metabolism | ||||
| Histidine metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Tryptophan metabolism | ||||
| Drug metabolism - cytochrome P450 | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Dopaminergic synapse | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5-Hydroxytryptamine degredation | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| WikiPathways | Tryptophan metabolism | |||
| Dopamine metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1273-9. | |||
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