Drug Information
Drug General Information | Top | |||
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Drug ID |
D0I7IA
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Former ID |
DNC009041
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Drug Name |
5'-Deoxy-5'-dimethylsulfonioadenosine chloride
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Synonyms |
SCHEMBL952519
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H18ClN5O3S
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Canonical SMILES |
C[S+](C)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O.[Cl-]
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InChI |
1S/C12H18N5O3S.ClH/c1-21(2)3-6-8(18)9(19)12(20-6)17-5-16-7-10(13)14-4-15-11(7)17;/h4-6,8-9,12,18-19H,3H2,1-2H3,(H2,13,14,15);1H/q+1;/p-1/t6-,8-,9-,12-;/m1./s1
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InChIKey |
UQRXECZPKCIHRJ-OUTCZKRVSA-M
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | S-adenosylmethionine decarboxylase proenzyme (AMD1) | Target Info | Inhibitor | [1] |
BioCyc | Methionine salvage cycle III | |||
Spermine biosynthesis | ||||
Spermidine biosynthesis | ||||
KEGG Pathway | Cysteine and methionine metabolism | |||
Arginine and proline metabolism | ||||
Metabolic pathways | ||||
NetPath Pathway | EGFR1 Signaling Pathway | |||
Pathwhiz Pathway | Spermidine and Spermine Biosynthesis | |||
Methionine Metabolism | ||||
WikiPathways | Metabolism of amino acids and derivatives |
References | Top | |||
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REF 1 | New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues ... J Med Chem. 2009 Mar 12;52(5):1388-407. |
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