Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I4TH
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| Former ID |
DCL001186
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| Drug Name |
GDC-0068
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| Synonyms |
RG7440
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| Drug Type |
Small molecular drug
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| Indication | Breast cancer [ICD-11: 2C60-2C65] | Phase 3 | [1] | |
| Colorectal cancer [ICD-11: 2B91.Z] | Phase 3 | [1] | ||
| Prostate cancer [ICD-11: 2C82.0; ICD-9: 185] | Phase 3 | [2] | ||
| Gastric adenocarcinoma [ICD-11: 2B72; ICD-9: 151] | Phase 2 | [3] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 2 | [4] | ||
| Company |
Genentech
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H32ClN5O2
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| Canonical SMILES |
CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
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| InChI |
1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1
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| InChIKey |
GRZXWCHAXNAUHY-NSISKUIASA-N
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| CAS Number |
CAS 1001264-89-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:95089
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Clinical pipeline report, company report or official report of Roche. | |||
| REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 4 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031868) | |||
| REF 5 | Clinical pipeline report, company report or official report of Genentech (2011). | |||
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