Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H1TG
|
|||
| Former ID |
DNCL003629
|
|||
| Drug Name |
ISIS-CRPRx
|
|||
| Indication | Coronary artery disease [ICD-11: BA80; ICD-10: I25.1, I25.4] | Phase 2 | [1] | |
| Company |
ISIS pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CRP messenger RNA (CRP mRNA) | Target Info | Modulator | [2] |
| NetPath Pathway | Leptin Signaling Pathway | |||
| Pathway Interaction Database | IL6-mediated signaling events | |||
| WikiPathways | IL-6 signaling pathway | |||
| Human Complement System | ||||
| Complement cascade | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024563) | |||
| REF 2 | Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies. J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):49-60. | |||
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