Drug Information
Drug General Information | Top | |||
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Drug ID |
D0GW5H
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Drug Name |
Polyhydroxy benzamide derivative 5
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Synonyms |
PMID26815044-Compound-57
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Drug Type |
Small molecular drug
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Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
Melasma [ICD-11: ED60.1] | Patented | [1] | ||
Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
Structure |
Download2D MOL |
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Formula |
C25H29NO4
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Canonical SMILES |
COC1=C(C=C(C=C1)C(=O)NCC2=C(C=C(C=C2)O)O)C34CC5CC(C3)CC(C5)C4
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InChI |
1S/C25H29NO4/c1-30-23-5-3-18(24(29)26-14-19-2-4-20(27)10-22(19)28)9-21(23)25-11-15-6-16(12-25)8-17(7-15)13-25/h2-5,9-10,15-17,27-28H,6-8,11-14H2,1H3,(H,26,29)
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InChIKey |
MZAJLDVRKVEVKU-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. |
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