Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E0GW
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| Former ID |
DIB005064
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| Drug Name |
BVT-3498
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| Synonyms |
AMG-311
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| Indication | Metabolic disorder [ICD-11: 5C50-5D2Z; ICD-10: E70-E90; ICD-9: 270-279] | Terminated | [1] | |
| Company |
Swedish Orphan Biovitrum AB
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| Structure |
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Download2D MOL |
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| Formula |
C16H18ClN3O4S2
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| Canonical SMILES |
CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=NC(=CS2)CCN3CCOCC3=O
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| InChI |
1S/C16H18ClN3O4S2/c1-11-13(17)3-2-4-14(11)26(22,23)19-16-18-12(10-25-16)5-6-20-7-8-24-9-15(20)21/h2-4,10H,5-9H2,1H3,(H,18,19)
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| InChIKey |
WZFZJEPHYDDFCT-UHFFFAOYSA-N
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| CAS Number |
CAS 376641-49-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Current and future drug targets in weight management. Pharm Res. 2011 Aug;28(8):1792-818. | |||
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