Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0DX8A
|
|||
Former ID |
DNC007869
|
|||
Drug Name |
6-chloro-5-propylpyrimidine-2,4(1H,3H)-dione
|
|||
Synonyms |
6-chloro-5-propylpyrimidine-2,4(1H,3H)-dione; 19030-76-3; 5-propyl-6-chloro-uracil; CHEMBL394425; BDBM20055; 5-Substituted-6-chlorouracil, 5b
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C7H9ClN2O2
|
|||
Canonical SMILES |
CCCC1=C(NC(=O)NC1=O)Cl
|
|||
InChI |
1S/C7H9ClN2O2/c1-2-3-4-5(8)9-7(12)10-6(4)11/h2-3H2,1H3,(H2,9,10,11,12)
|
|||
InChIKey |
DTSULQDNDBSJQV-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 19030-76-3
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Thymidine phosphorylase (TYMP) | Target Info | Inhibitor | [1] |
BioCyc | Pyrimidine deoxyribonucleosides degradation | |||
KEGG Pathway | Pyrimidine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Bladder cancer | ||||
NetPath Pathway | TSH Signaling Pathway | |||
Pathwhiz Pathway | Pyrimidine Metabolism | |||
WikiPathways | Bladder Cancer | |||
Metabolism of nucleotides | ||||
Fluoropyrimidine Activity |
References | Top | |||
---|---|---|---|---|
REF 1 | Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase. J Med Chem. 2007 Nov 29;50(24):6016-23. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.