Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D0QT
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| Drug Name |
Pyrido[1,2,4]triazolo[4,3-a]pyrazine derivative 2
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| Synonyms |
PMID27321640-Compound-55
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|
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| Drug Type |
Small molecular drug
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| Company |
LUNDBECK & CO AS H [DKJOERGENSEN MORTEN [DKBRUUN ANNE TECHAU [DKRASMUSSEN LARS KYHN [DK]
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H10ClN5
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| Canonical SMILES |
CC1=NC2=C(C=CN=C2)N3C1=NN=C3C4=CC=CC=C4Cl
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| InChI |
1S/C15H10ClN5/c1-9-14-19-20-15(10-4-2-3-5-11(10)16)21(14)13-6-7-17-8-12(13)18-9/h2-8H,1H3
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| InChIKey |
NUACZBDSBLGPGS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 10A (PDE10) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 2A (PDE2A) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Phosphodiesterase 10A (PDE10) | Target's Patent Info | [1] | |
| Phosphodiesterase 2A (PDE2A) | Target's Patent Info | [1] | ||
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46. | |||
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