Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B9EN
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| Former ID |
DCL000419
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| Drug Name |
Aleglitazar
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| Synonyms |
RO7; Aleglitazar (USAN); 2-methoxy-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]benzothiophen-7-yl]propanoic Acid
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| Drug Type |
Small molecular drug
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| Indication | Type-2 diabetes [ICD-11: 5A11; ICD-9: 250] | Discontinued in Phase 3 | [1], [2] | |
| Company |
Roche
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| Structure |
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Download2D MOL |
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| Formula |
C24H23NO5S
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| Canonical SMILES |
CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=C4C=CSC4=C(C=C3)CC(C(=O)O)OC
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| InChI |
1S/C24H23NO5S/c1-15-19(25-23(30-15)16-6-4-3-5-7-16)10-12-29-20-9-8-17(14-21(28-2)24(26)27)22-18(20)11-13-31-22/h3-9,11,13,21H,10,12,14H2,1-2H3,(H,26,27)/t21-/m0/s1
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| InChIKey |
DAYKLWSKQJBGCS-NRFANRHFSA-N
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| CAS Number |
CAS 475479-34-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
15279780, 22652721, 35445984, 74374212, 74374213, 74671516, 96025528, 99444954, 103652550, 104120360, 126665625, 134339048, 135216342, 136349978, 137156430, 141536129, 160969520, 163620807, 163686133, 170501031, 175427152, 176250129, 178103977, 185988952, 198964037, 215784940, 223535497, 223670924, 223800328, 226798862, 241083923, 245949369, 252477574
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7405). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017317) | |||
| REF 3 | Clinical pipeline report, company report or official report of Roche (2009). | |||
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