Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0B7CZ
|
|||
Former ID |
DIB012664
|
|||
Drug Name |
Teloxantrone
|
|||
Synonyms |
Moxantrazole; Teloxantrone hydrochloride; Teloxantrone hydrochloride hydrate; DuP-937; PD-113309
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 1 | [1] | |
Company |
Parke-Davis & Co
|
|||
Structure |
Download2D MOL |
|||
Formula |
C21H25N5O4
|
|||
Canonical SMILES |
CNCCN=C1C=CC2=C3C1=C(C4=C(C=CC(=O)C4=C3NN2CCNCCO)O)O
|
|||
InChI |
1S/C21H25N5O4/c1-22-6-7-24-12-2-3-13-17-16(12)21(30)19-15(29)5-4-14(28)18(19)20(17)25-26(13)10-8-23-9-11-27/h2-5,22-23,25,27,29-30H,6-11H2,1H3
|
|||
InChIKey |
WOPAVGQTOMNFGS-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 91441-48-4
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | DNA topoisomerase II (TOP2) | Target Info | Modulator | [2] |
References | Top | |||
---|---|---|---|---|
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000732) | |||
REF 2 | Topoisomerase II inhibition and cytotoxicity of the anthrapyrazoles DuP 937 and DuP 941 (Losoxantrone) in the National Cancer Institute preclinical... J Natl Cancer Inst. 1994 Aug 17;86(16):1239-44. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.