Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0AX9S
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| Former ID |
DIB008851
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| Drug Name |
GW-409544
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| Synonyms |
GW-409544X; GW-544; GW-6471; Lipid regulators, Ligand/Glaxo
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| Drug Type |
Small molecular drug
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| Indication | Hyperlipidaemia [ICD-11: 5C80; ICD-10: E78.5] | Phase 1 | [1], [2] | |
| Company |
Ligand Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C31H30N2O5
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| Canonical SMILES |
CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)CC(C(=O)O)NC(=CC(=O)C4=CC=CC=C4)C
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| InChI |
1S/C31H30N2O5/c1-21(19-29(34)24-9-5-3-6-10-24)32-28(31(35)36)20-23-13-15-26(16-14-23)37-18-17-27-22(2)38-30(33-27)25-11-7-4-8-12-25/h3-16,19,28,32H,17-18,20H2,1-2H3,(H,35,36)/b21-19-/t28-/m0/s1
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| InChIKey |
GGUVRMBIEPYOKL-WMVCGJOFSA-N
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| CAS Number |
CAS 258345-41-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:79990
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3440). | |||
| REF 2 | Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach. PLoS One. 2012;7(6):e38546. | |||
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