Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A2AF
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| Former ID |
DNC003202
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| Drug Name |
N-Methyl-N-Propargyl-1(R)-Aminoindan
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| Synonyms |
124192-87-6; N-METHYL-N-PROPARGYL-1(R)-AMINOINDAN; (R)-N-Methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine; (R)-2,3-Dihydro-N-methyl-N-2-propynyl-1H-inden-1-amine; (R)-N-Methyl-N-(2-propynyl)-2,3-dihydroinden-1-amine; UNII-1Y7XS87IZR; 1Y7XS87IZR; CHEMBL436947; (1R)-N-methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine; N-[(1S)-2,3-DIHYDRO-1H-INDEN-1-YL]-N-METHYL-N-PROP-2-YNYLAMINE; R-MPAI; N-Methyl-N-2-propynyl-1-indanamine, (R)-; AC1NRD15; 1H-Inden-1-amine,2,3-dihydro-N-methyl-N-2-propyn-1-yl-, (1R)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H15N
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| Canonical SMILES |
CN(CC#C)C1CCC2=CC=CC=C12
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| InChI |
1S/C13H15N/c1-3-10-14(2)13-9-8-11-6-4-5-7-12(11)13/h1,4-7,13H,8-10H2,2H3/t13-/m1/s1
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| InChIKey |
CSVGVHNFFZWQJU-CYBMUJFWSA-N
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| CAS Number |
CAS 124192-87-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation via tryptamine | ||||
| Dopamine degradation | ||||
| Putrescine degradation III | ||||
| Noradrenaline and adrenaline degradation | ||||
| KEGG Pathway | Glycine, serine and threonine metabolism | |||
| Arginine and proline metabolism | ||||
| Histidine metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Tryptophan metabolism | ||||
| Drug metabolism - cytochrome P450 | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Dopaminergic synapse | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5-Hydroxytryptamine degredation | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| WikiPathways | Tryptophan metabolism | |||
| Dopamine metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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