Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09KDS
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| Former ID |
DNC007936
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| Drug Name |
Adamantan-1-yl-(4-ethyl-piperazin-1-yl)-methanone
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| Synonyms |
CHEMBL396928; AC1N8RTC; 1-adamantyl-(4-ethylpiperazin-1-yl)methanone; Oprea1_784934; adamantan-1-yl-(4-ethyl-piperazin-1-yl)-methanone; MolPort-005-510-679; BDBM50207776
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H28N2O
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| Canonical SMILES |
CCN1CCN(CC1)C(=O)C23CC4CC(C2)CC(C4)C3
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| InChI |
1S/C17H28N2O/c1-2-18-3-5-19(6-4-18)16(20)17-10-13-7-14(11-17)9-15(8-13)12-17/h13-15H,2-12H2,1H3
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| InChIKey |
XOWWNQSYPPTVEH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. | |||
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