Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09IEE
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| Former ID |
DAP001189
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| Drug Name |
Prednicarbate
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| Synonyms |
Dermatop; Peitel; Dermatop (TN); Hoe-777; S-77 0777; S-770777; Prednicarbate (USP/INN); [2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Approved | [1], [2] | |
| Therapeutic Class |
Antiinflammatory Agents
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| Structure |
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Download2D MOL |
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| Formula |
C27H36O8
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| Canonical SMILES |
CCC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)OC(=O)OCC
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| InChI |
1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
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| InChIKey |
FNPXMHRZILFCKX-KAJVQRHHSA-N
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| CAS Number |
CAS 73771-04-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
11467072, 11468192, 11486640, 12013808, 14810426, 17190443, 43333414, 47207264, 47574670, 47871009, 47945107, 48244692, 49699264, 50124068, 50655143, 56463553, 57371370, 71825010, 85787547, 92125934, 92720065, 103770369, 103914660, 114951144, 121363605, 124799601, 126620396, 126651370, 134223290, 135012724, 137240385, 144204238, 163835804, 164232786, 164814618, 175267150, 175612124, 179149412, 196105692, 223365940, 223680208, 226396028, 252356176
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| ChEBI ID |
CHEBI:135791
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| ADReCS Drug ID | BADD_D01830 | |||
| SuperDrug ATC ID |
D07AC18
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| SuperDrug CAS ID |
cas=073771047
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid hormone receptor ERR (ESRR) | Target Info | Modulator | [3] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7605). | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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