Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09ICC
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| Former ID |
DNC002813
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| Drug Name |
SB220025
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| Synonyms |
SB220025; 3erk; sb 220025; SB-220025; CHEMBL274064; 165806-53-1; CHEBI:82713; 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine; 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE; SB4; 5-(2-Amino-4-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinlyl)imidazole; 4-[5-(4-fluorophenyl)-3-(4-piperidyl)imidazol-4-yl]pyrimidin-2-amine; SB-220025-A; 1-(4-piperidinyl)-4-(4-fluorophenyl)-5-(2-(amino)-4-pyrimidinyl)imidazole
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| Drug Type |
Small molecular drug
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| Indication | Arthritis [ICD-11: FA20] | Terminated | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H19FN6
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| Canonical SMILES |
C1CNCCC1N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F
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| InChI |
1S/C18H19FN6/c19-13-3-1-12(2-4-13)16-17(15-7-10-22-18(20)24-15)25(11-23-16)14-5-8-21-9-6-14/h1-4,7,10-11,14,21H,5-6,8-9H2,(H2,20,22,24)
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| InChIKey |
VSPFURGQAYMVAN-UHFFFAOYSA-N
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| CAS Number |
CAS 165806-53-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
825165, 5591038, 7890383, 8153175, 14827055, 26718514, 26759481, 29217658, 29224226, 46391555, 46394351, 46506944, 46515546, 57322636, 79465511, 99302802, 103176356, 103905253, 104308454, 124349771, 124349772, 126408090, 129521105, 134347675, 137092499, 142405669, 160967374, 163016120, 163687373, 163826837, 163826838, 163826842, 175607507, 176485413, 176485414, 178102660, 179148809, 204360495, 212343839, 223447434, 224493896, 226534849
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| ChEBI ID |
CHEBI:82713
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6038). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010505) | |||
| REF 3 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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