Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09EIX
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| Drug Name |
PMID26936077-Compound-13
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| Drug Type |
Small molecular drug
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| Indication | Gastric ulcer [ICD-11: DA60] | Patented | [1] | |
| Metabolic disorder [ICD-11: 5C50-5D2Z; ICD-10: IV] | Patented | [1] | ||
| Type-2 diabetes [ICD-11: 5A11] | Patented | [1] | ||
| Company |
THE UNIVERSITY OF QUEENSLAND FAIRLIE, David Paul LIU, Ligong YAU, Mei-Kwan SUEN, Jacky Yung REID, Robert LOHMAN, Rink-Jan IYER, Abishek Venkatasubramanian LIM, Junxian BROWN, Lindsay CharleThe University of Queensland
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| Structure |
 |
Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Proteinase activated receptor 2 (PAR2) | Target Info | Antagonist | [1] |
| Target's Patent Info | Proteinase activated receptor 2 (PAR2) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| African trypanosomiasis | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83. | |||
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