Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09EAO
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| Former ID |
DNC000899
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| Drug Name |
LY214352
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| Synonyms |
8-Chloro-4-(2-chloro-4-fluorophenoxy)quinoline; 124495-31-4; Quinoline,8-chloro-4-(2-chloro-4-fluorophenoxy)-; LY214352; AC1L2WYE; ACMC-1C12P; SCHEMBL7044612; CTK4B3930; DTXSID10154407; ZXLMSTBJMZJAAH-UHFFFAOYSA-N; LY-214352; 8-chloro-4-(2-chloro-4-fluorophenoxy) quinoline
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H8Cl2FNO
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| Canonical SMILES |
C1=CC2=C(C=CN=C2C(=C1)Cl)OC3=C(C=C(C=C3)F)Cl
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| InChI |
1S/C15H8Cl2FNO/c16-11-3-1-2-10-13(6-7-19-15(10)11)20-14-5-4-9(18)8-12(14)17/h1-8H
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| InChIKey |
ZXLMSTBJMZJAAH-UHFFFAOYSA-N
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| CAS Number |
CAS 124495-31-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of a new antifungal target site through a dual biochemical and molecular-genetics approach. Curr Genet. 1996 Jul 31;30(2):159-65. | |||
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