Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09DXN
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| Former ID |
DIB019760
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| Drug Name |
D-kynurenine
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| Synonyms |
D-Kynurenine; 13441-51-5; (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; UNII-DK8PQD0WC5; DK8PQD0WC5; CHEBI:86262; (2R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid; K-8980; Kynurenine, D-; D-2-Amino-4-[2-aminophenyl]-4-oxobutanoic acid; D-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; D-KYN; D-Kynurenine, free base; AC1LMC0V; GTPL5799; SCHEMBL13969610; CHEMBL1233899; Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, (R)-; CTK8C4802; DTXSID50360767; Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, (alphaR)-; ZINC901103
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C10H12N2O3
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| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N
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| InChI |
1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1
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| InChIKey |
YGPSJZOEDVAXAB-MRVPVSSYSA-N
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| CAS Number |
CAS 13441-51-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9091606, 11113257, 24896220, 26756701, 42719507, 49747908, 50892774, 57408929, 91704652, 99373257, 99453914, 104250062, 110252413, 118050690, 124385442, 129793001, 152030448, 160840661, 162227360, 163099716, 163404890, 164785456, 172087336, 178102424, 204431463, 223533508, 238957647, 241027781, 241177892, 241178033, 249730941, 249819172, 252162401, 252400312
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| ChEBI ID |
CHEBI:86262
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hydroxycarboxylic acid receptor 3 (HCAR3) | Target Info | Agonist | [2] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5799). | |||
| REF 2 | Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3930-4. | |||
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