Drug Information
Drug General Information | Top | |||
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Drug ID |
D08ZWM
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Former ID |
DNC011734
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Drug Name |
PSILOCIN
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Synonyms |
PSILOCIN; 4-Hydroxy-N,N-dimethyltryptamine; Psilocine; Psilotsin; 520-53-6; Psilocyn; 3-[2-(Dimethylamino)ethyl]-1H-indol-4-ol; 3-(2-(Dimethylamino)ethyl)indol-4-ol; UNII-CMS88KUW0G; N,N-Dimethyl-4-Hydroxytryptamine; CX-59; EINECS 208-296-5; CMS88KUW0G; BRN 0160503; CHEMBL65547; CHEBI:8613; DEA No. 7438; 3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol; NCGC00247728-01; P-7800; 1H-Indol-4-ol, 3-[2-(dimethylamino)ethyl]-; INDOL-4-OL, 3-(2-(DIMETHYLAMINO)ETHYL)-; Indol-4-ol, 3-[2-(dimethylamino)ethyl]-; Psilocin solution; AC1L1JCI; 4-OH-DMT
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C12H16N2O
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Canonical SMILES |
CN(C)CCC1=CNC2=C1C(=CC=C2)O
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InChI |
1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
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InChIKey |
SPCIYGNTAMCTRO-UHFFFAOYSA-N
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CAS Number |
CAS 520-53-6
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:8613
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Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. |
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