Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08EMW
|
|||
| Drug Name |
Carbamate derivative 15
|
|||
| Synonyms |
PMID29053063-Compound-10g
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
PFIZER INC
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H29F3N2O6S
|
|||
| Canonical SMILES |
CC(C)N(C1CC2(CCN(CC2)C(=O)OC(CO)C(F)(F)F)OC1)S(=O)(=O)C3=CC=CC=C3
|
|||
| InChI |
1S/C21H29F3N2O6S/c1-15(2)26(33(29,30)17-6-4-3-5-7-17)16-12-20(31-14-16)8-10-25(11-9-20)19(28)32-18(13-27)21(22,23)24/h3-7,15-16,18,27H,8-14H2,1-2H3/t16-,18-/m1/s1
|
|||
| InChIKey |
FNERRHFFFPJRAG-SJLPKXTDSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoglyceride lipase (MAGL) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Monoglyceride lipase (MAGL) | Target's Patent Info | [1] | |
| BioCyc | Triacylglycerol degradation | |||
| KEGG Pathway | Glycerolipid metabolism | |||
| Metabolic pathways | ||||
| Retrograde endocannabinoid signaling | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Reactome | Acyl chain remodeling of DAG and TAG | |||
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Glycerophospholipid biosynthesis | ||||
| GPCR downstream signaling | ||||
| Effects of PIP2 hydrolysis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).Expert Opin Ther Pat. 2017 Dec;27(12):1341-1351. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.