Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07UCQ
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| Former ID |
DNC010204
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| Drug Name |
Sodium phenylaminomethanesulfonate
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| Synonyms |
Sodium anilinomethanesulfonate; Sodium anilinomethanesulphonate; Methanesulfonic acid, (phenylamino)-, monosodium salt; 26021-90-9; Aniline-N-methylsulfonic acid,Na salt; Methanesulfonic acid, 1-(phenylamino)-, sodium salt (1:1); Anilinomethanesulfonate sodium salt; Anilinomethanesulfonic acid, sodium salt; W-110647; (Phenylamino)methanesulfonic acid, sodium salt; Phenylaminomethanesulfonic acid, monosodium salt; Sodium phenylaminomethanesulfonate; EINECS 247-417-6; NSC 57030; Anilinomethanesulfonic acid, monosodium salt
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H8NNaO3S
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| Canonical SMILES |
C1=CC=C(C=C1)NCS(=O)(=O)[O-].[Na+]
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| InChI |
1S/C7H9NO3S.Na/c9-12(10,11)6-8-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,9,10,11);/q;+1/p-1
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| InChIKey |
AJSINQAAKNYUDA-UHFFFAOYSA-M
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| CAS Number |
CAS 26021-90-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase XII (CA-XII) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Reversible Hydration of Carbon Dioxide | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the... Bioorg Med Chem. 2009 Oct 15;17(20):7093-9. | |||
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