Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07NYQ
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| Former ID |
DNC000435
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| Drug Name |
Cinchoninic acid
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| Synonyms |
Quinoline-4-carboxylic acid; 486-74-8; 4-Quinolinecarboxylic acid; CINCHONINIC ACID; 4-Carboxyquinoline; Cinchonic acid; USAF D-2; NSC 13138; EINECS 207-640-1; MFCD00006782; Quinoline-4-Carboxylicacid; BRN 0005224; 4-QuinolinecarboxylicAcid; Cinchoninsaure; PubChem5843; Chinolin-4-carbonsaeure; AC1L1USE; Maybridge1_002367; quinoline4-carboxylic acid; 4-quinoline carboxylic acid; ACMC-1AM77; WLN: T66 BNJ EVQ; Oprea1_466681; KSC171Q1F; 5-22-03-00204 (Beilstein Handbook Reference); SCHEMBL228713; DivK1c_001119; AC1Q72O9; CHEBI:18311
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H7NO2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CC=N2)C(=O)O
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| InChI |
1S/C10H7NO2/c12-10(13)8-5-6-11-9-4-2-1-3-7(8)9/h1-6H,(H,12,13)
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| InChIKey |
VQMSRUREDGBWKT-UHFFFAOYSA-N
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| CAS Number |
CAS 486-74-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8649, 77664, 610017, 3160883, 6703459, 8143818, 8157388, 11336294, 11380638, 11511653, 11536925, 15091447, 24850356, 24853584, 29228764, 47291458, 48435581, 49903711, 50673701, 53795860, 57326069, 85279985, 87363394, 87575582, 92254838, 99226469, 104322763, 104818706, 117606988, 118049306, 121278031, 124395090, 125001062, 125236542, 125351288, 126579206, 126614053, 126659129, 126688806, 126697544, 126736664, 129512598, 131102438, 134339861, 134975685, 135702147, 136889823, 136908138, 136996447, 137027352
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| ChEBI ID |
CHEBI:18311
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76. | |||
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