Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07BKL
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| Former ID |
DIB003192
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| Drug Name |
KW-2170
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| Drug Type |
Small molecular drug
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| Indication | Breast cancer [ICD-11: 2C60-2C65] | Discontinued in Phase 2 | [1] | |
| Company |
Kyowa Hakko Kogyo Co Ltd
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| Structure |
 |
Download2D MOL
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| Formula |
C20H25Cl2N5O4
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| Canonical SMILES |
C1=CC(=C2C3=C1C(=NN3C4=C(C=CC(=O)C4=C2O)O)CNCCO)NCCCN.Cl.Cl
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| InChI |
1S/C20H23N5O4.2ClH/c21-6-1-7-23-12-3-2-11-13(10-22-8-9-26)24-25-18(11)16(12)20(29)17-14(27)4-5-15(28)19(17)25;;/h2-5,22-23,26,28-29H,1,6-10,21H2;2*1H
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| InChIKey |
FSJDQJHSJAGEJV-UHFFFAOYSA-N
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| CAS Number |
CAS 207862-44-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase II (TOP2) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004178) | |||
| REF 2 | KW-2170 (Kyowa Hakko Kogyo). IDrugs. 2002 Oct;5(10):1000-3. | |||
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