Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06PVN
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| Former ID |
DIB015338
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| Drug Name |
R-65
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| Synonyms |
PGN-1473; R-65 (myometrial disorders), Asterand; R-65 (myometrial disorders), Pharmagene
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| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Investigative | [1] | |
| Company |
Pharmagene plc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E2 receptor EP2 (PTGER2) | Target Info | Modulator | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Renin secretion | ||||
| Pathways in cancer | ||||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Ovarian Infertility Genes | ||||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 341). | |||
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