Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05YJP
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| Former ID |
DNC007066
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| Drug Name |
Ethyl 3-(biphenyl-3-ylamino)-2-cyanoacrylate
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| Synonyms |
CHEMBL387254; ethyl (2z)-3-(biphenyl-3-ylamino)-2-cyanoprop-2-enoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H16N2O2
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| Canonical SMILES |
CCOC(=O)C(C=NC1=CC=CC(=C1)C2=CC=CC=C2)C#N
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| InChI |
1S/C18H16N2O2/c1-2-22-18(21)16(12-19)13-20-17-10-6-9-15(11-17)14-7-4-3-5-8-14/h3-11,13,16H,2H2,1H3
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| InChIKey |
ADNKWYMTGWSRNK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase. J Med Chem. 2007 Jan 25;50(2):186-91. | |||
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