Drug Information
Drug General Information | Top | |||
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Drug ID |
D05DSL
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Drug Name |
PMID27376512-Compound-Table1Example16
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Drug Type |
Small molecular drug
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Company |
IKERCHEM S L [ESUNIV DEL PA S VASCO [ES]
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Structure |
Download2D MOL |
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Formula |
C22H15F2NO3
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Canonical SMILES |
C1=CC(=CC=C1C2=CN(C3=C2C(=CC(=C3)F)F)CC(=O)C4=CC=C(C=C4)O)O
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InChI |
1S/C22H15F2NO3/c23-15-9-19(24)22-18(13-1-5-16(26)6-2-13)11-25(20(22)10-15)12-21(28)14-3-7-17(27)8-4-14/h1-11,26-27H,12H2
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InChIKey |
ZSLQOKAZOXSRMM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target Info | Inhibitor | [1] |
Target's Patent Info | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target's Patent Info | [1] | |
KEGG Pathway | Cysteine and methionine metabolism | |||
Metabolic pathways | ||||
MicroRNAs in cancer | ||||
Pathwhiz Pathway | Methionine Metabolism | |||
Pathway Interaction Database | Regulation of retinoblastoma protein | |||
Reactome | PRC2 methylates histones and DNA | |||
NoRC negatively regulates rRNA expression | ||||
DNA methylation | ||||
WikiPathways | Trans-sulfuration and one carbon metabolism | |||
Retinoblastoma (RB) in Cancer | ||||
One Carbon Metabolism | ||||
Trans-sulfuration pathway |
References | Top | |||
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REF 1 | DNA methyltransferase inhibitors: an updated patent review (2012-2015).Expert Opin Ther Pat. 2016 Sep;26(9):1017-30. |
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