Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05AWP
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| Drug Name |
Moxidectin
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| Synonyms |
Moxidectin; ProHeart 6; UNII-NGU5H31YO9; Cydectin; NGU5H31YO9; Moxidectine [INN-French]; Moxidectinum [INN-Latin]; Moxidectina [INN-Spanish]; C37H53NO8; Moxidectina; Moxidectine; Moxidectinum; Moxidectin [USAN:INN:BAN]
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| Indication | Onchocerciasis [ICD-11: 1F6A; ICD-10: B73] | Approved | [1] | |
| River blindness [ICD-11: 1F6A.0; ICD-10: B73] | Approved | [2] | ||
| Company |
Medicines Development for Global Health
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| Structure |
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Download2D MOL |
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| Formula |
C37H53NO8
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| Canonical SMILES |
CC1CC(=CCC2CC(CC3(O2)CC(=NOC)C(C(O3)C(=CC(C)C)C)C)OC(=O)C4C=C(C(C5C4(C(=CC=C1)CO5)O)O)C)C
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| InChI |
1S/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31+/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1
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| InChIKey |
YZBLFMPOMVTDJY-LSGXYNIPSA-N
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| CAS Number |
CAS 113507-06-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid receptor (GAR) | Target Info | Modulator | [2] |
| Onchocerca Glutamate-gated chloride channel (Onchoc GluCl) | Target Info | Modulator | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2018. Application Number: (ANDA) 210867. | |||
| REF 2 | 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89. | |||
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