Drug Information
Drug General Information | Top | |||
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Drug ID |
D04QKU
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Former ID |
DIB011780
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Drug Name |
RG-7090
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Synonyms |
RO-4917523; Antidepressant (oral), Hoffmann-La Roche; MGluR5 antagonist (depression/fragile X syndrome, oral), Roche
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Drug Type |
Small molecular drug
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Indication | Fragile X syndrome [ICD-11: LD55; ICD-10: Q99.2] | Phase 2 | [1] | |
Company |
F Hoffmann-La Roche Ltd
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Structure |
Download2D MOL |
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Formula |
C18H13ClFN3
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Canonical SMILES |
CC1=C(N=C(N1C2=CC=C(C=C2)F)C)C#CC3=CC(=NC=C3)Cl
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InChI |
1S/C18H13ClFN3/c1-12-17(8-3-14-9-10-21-18(19)11-14)22-13(2)23(12)16-6-4-15(20)5-7-16/h4-7,9-11H,1-2H3
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InChIKey |
UPZWINBEAHDTLA-UHFFFAOYSA-N
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CAS Number |
CAS 802906-73-6
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PubChem Compound ID |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01750957) A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome. U.S. National Institutes of Health. | |||
REF 2 | The challenges of clinical trials in fragile X syndrome. Psychopharmacology (Berl) 2014; 231(6): 1237-1250. |
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