Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04MLE
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| Former ID |
DIB000819
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| Drug Name |
GKA-23
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| Synonyms |
GKA-21; GKA-22; GKA-30; GKA-31; GKA-50; GKA-60; Glucokinase activators (diabetes); Glucokinase activators (diabetes), AstraZeneca
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| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Investigative | [1] | |
| Company |
AstraZeneca plc
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| Structure |
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Download2D MOL |
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| Formula |
C21H20N6O3S2
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| Canonical SMILES |
CC1=NC(=C(C=C1)OC2=C(N=CC(=C2)SC3=CC=CC=N3)NC4=NC(=NS4)C(CO)O)C
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| InChI |
1S/C21H20N6O3S2/c1-12-6-7-16(13(2)24-12)30-17-9-14(31-18-5-3-4-8-22-18)10-23-20(17)26-21-25-19(27-32-21)15(29)11-28/h3-10,15,28-29H,11H2,1-2H3,(H,23,25,26,27)/t15-/m1/s1
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| InChIKey |
NARRNXGFBLOLIN-OAHLLOKOSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2798). | |||
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