Drug Information
Drug General Information | Top | |||
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Drug ID |
D04LGV
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Former ID |
DNC009868
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Drug Name |
1-(4-ethylphenylsulfonyl)-4-phenylazepan-4-ol
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Synonyms |
CHEMBL562684; 1-(4-ethylphenylsulfonyl)-4-phenylazepan-4-ol; SCHEMBL12549978
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C20H25NO3S
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Canonical SMILES |
CCC1=CC=C(C=C1)S(=O)(=O)N2CCCC(CC2)(C3=CC=CC=C3)O
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InChI |
1S/C20H25NO3S/c1-2-17-9-11-19(12-10-17)25(23,24)21-15-6-13-20(22,14-16-21)18-7-4-3-5-8-18/h3-5,7-12,22H,2,6,13-16H2,1H3
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InChIKey |
BUVJJRPTSWXSAA-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolism of xenobiotics by cytochrome P450 | ||||
Metabolic pathways | ||||
Chemical carcinogenesis | ||||
NetPath Pathway | IL1 Signaling Pathway | |||
FSH Signaling Pathway | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
WikiPathways | Prostaglandin Synthesis and Regulation | |||
Metabolism of steroid hormones and vitamin D | ||||
Glucocorticoid & Mineralcorticoid Metabolism |
References | Top | |||
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REF 1 | The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4563-5. |
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