Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04LBT
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| Former ID |
DNC000229
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| Drug Name |
Antimycin A
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| Synonyms |
Antimycin A; Antipiricullin; Fintrol; Virosin; Antimycin A1b; antimycin A1; Caswell No. 052B; Antimycin-A; CCRIS 924; HSDB 6417; UNII-75G3NMU1TS; EPA Pesticide Chemical Code 006314; 75G3NMU1TS; CHEMBL211501; CHEBI:22584; 1397-94-0; (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate; 642-15-9; 116095-18-2; [(2r,3s,6s,7r,8r)-3-[(3-Formamido-2-Oxidanyl-Phenyl)carbonylamino]-8-Hexyl-2,6-Dimethyl-4,9-Bis(Oxidanylidene)-1,5-Dioxonan-7-Yl] 3-Methylbutanoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C28H40N2O9
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| Canonical SMILES |
CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C
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| InChI |
1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1
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| InChIKey |
UIFFUZWRFRDZJC-SBOOETFBSA-N
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| CAS Number |
CAS 1397-94-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
614296, 842107, 8161229, 15408397, 26754304, 26754305, 26754306, 29282954, 48484001, 49871310, 56310777, 56311298, 56312640, 56314043, 56314343, 57288654, 57328808, 80249517, 85240159, 99437140, 103494075, 104074665, 104335826, 117625454, 124558768, 124757233, 124883056, 124883057, 124883058, 125164037, 134980168, 135202724, 135363768, 137152320, 144115612, 152028624, 162220240, 164816521, 174007463, 175607931, 179149276, 184605758, 198966372, 198976814, 198979101, 206246459, 226571925, 247480488, 252300547, 252401136
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| ChEBI ID |
CHEBI:22584
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenase. Antimicrob Agents Chemother. 1995 Feb;39(2):325-8. | |||
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