Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04HZA
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| Former ID |
DNC006008
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| Drug Name |
2-(2-bromo-2-naphthamido)benzoic acid
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| Synonyms |
CHEMBL199574; SCHEMBL18120563; BDBM16096; 2-[(6-bromonaphthalene-2-)amido]benzoic acid; 2-{[(6-bromonaphthalen-2-yl)carbonyl]amino}benzoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H12BrNO3
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| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)O)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)Br
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| InChI |
1S/C18H12BrNO3/c19-14-8-7-11-9-13(6-5-12(11)10-14)17(21)20-16-4-2-1-3-15(16)18(22)23/h1-10H,(H,20,21)(H,22,23)
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| InChIKey |
KNVPXLPBRSRJCV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Bioorg Med Chem Lett. 2006 Jan 1;16(1):88-92. | |||
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